This collection documents the Highland Park Hospital. There are two series: Friends of Highland Park Hospital and Highland Park Hospital.

The first series holds reports and other materials created by the Friends of Highland Park Hospital and related organizations. The community funded hospital and its supporting organizations created and disseminated updates on the hospital's progress, events, and free general health information. The Hospital also had a Thrift Shop, run by the Highland Park Hospital Auxiliary. This series includes newsletters, annual reports, correspondence, pamphlets, and thrift shop information.

The second series, Highland Park Hospital, documents the Highland Park Hospital. It holds material to increase awareness and promote the Hospital. Annual reports, early birth records, correspondence, hospital development information, program information, pamphlets, newsletters, newspaper clippings, newspapers, photographs (images and negatives), and stock certificates comprise this collection.

The collection consists of photographs of Gertrude Knapmiller Ronzani, Floyd Presley, Theresa Slack, John Frantonius, Marie Knapmiller Frantonius, and John Peterson. Also included are a lady's lace cap, a booklet celebrating the 20th anniversary of the hospital in 1938, a postcard, and a photocopy of the fifteenth census of the United States of 1930, issued by the Department of Commerce - Bureau of the Census.